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Famotidine (Pepcid): MedlinePlus Drug Information

Tier 1: Established: peer-reviewed research or government health authority
Publisher: MedlinePlus (U.S. National Library of Medicine, NIH) · Published: August 7, 2026 · Accessed: August 7, 2026

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Claims this source supports

  • Famotidine (Pepcid) is in a class of medications called H2 blockers; it works by decreasing the amount of acid made in the stomach.
  • Prescription famotidine treats ulcers, GERD, and conditions of excess stomach acid; over-the-counter famotidine prevents and treats heartburn.
  • Common side effects include headache, dizziness, constipation, and diarrhea.
  • Tell your doctor if you have or have ever had kidney disease or trouble swallowing; do not take OTC famotidine longer than 2 weeks unless a doctor says so.